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Matched nested case-control

A matched nested case-control study is an efficient observational design embedded within a defined cohort. When a participant develops the outcome of interest (a case), a small number of controls are sampled from those still at risk at that moment and matched to the case on key variables such as age, sex, or calendar time. This design preserves the temporal structure of the underlying cohort while sharply reducing the cost of exposure measurement.

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Matched Nested Case-Control Study

Taxonomisk metodpost · process-pipeline / epidemiology

Rothman, K.J., Greenland, S., & Lash, T.L. (2008). Modern Epidemiology (3rd ed.). Lippincott Williams & Wilkins. · ISBN 978-0781755641
Thomas, D.B. (1977). Methodology for assessing interaction in epidemiological studies of matched pairs. Biometrics, 33(3), 463-470. · URL

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