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	Etika istraživanja na životinjama	Belmont Report
Oblast	Etika istraživanja	Etika istraživanja
Porodica	Process / pipeline	Process / pipeline
Godina nastanka	1959	1979
Tvorac	Russell & Burch (1959); EU Directive 2010/63/EU; NIH, USDA, international adoption	National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research (US DHEW)
Tip	Framework	Framework
Temeljni izvor	Russell, W.M.S. & Burch, R.L. (1959). The Principles of Humane Experimental Technique. Methuen.	National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research. (1979). The Belmont Report: Ethical Principles and Guidelines for the Protection of Human Subjects of Research. Department of Health, Education, and Welfare.
Drugi nazivi	3Rs Framework, Animal Welfare Principles, Animal Research Ethics	Belmont Principles, Three Ethical Principles
Srodne	3	5
Sažetak	The 3Rs (Replacement, Reduction, Refinement) is the ethical framework governing humane animal research, established by Russell and Burch (1959) and now adopted globally by research institutions, funding agencies, and regulatory bodies. The 3Rs require researchers to: replace animal research with non-animal methods where possible, reduce the number of animals used through rigorous design, and refine experimental procedures to minimize animal suffering. Implementation of the 3Rs is now mandatory in most jurisdictions through Institutional Animal Care and Use Committees (IACUCs), EU Directive 2010/63/EU, and NIH policy.	The Belmont Report (1979) is the foundational US ethical framework for human subjects research, established by the National Commission following the Tuskegee Syphilis Study scandal. It articulates three core principles—Respect for Persons, Beneficence, and Justice—that form the basis for institutional review and regulatory oversight of human research globally. Every researcher conducting human studies must understand and apply these principles.