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OdborKlinický výskumKlinický výskum
RodinaProcess / pipelineProcess / pipeline
Rok vzniku1970s-1980s1950s-1970s
TvorcaDonald Acheson, Olli Miettinen, and others in modern epidemiologyJerome L. Schlesselman, Brian MacMahon, Thomas Pugh
TypResearch DesignResearch Design
Pôvodný zdrojMiettinen, O. S. (1976). Estimability and estimation in case-referent studies. American Journal of Epidemiology, 103(2), 226–235. DOI ↗Schlesselman, J. J. (1982). Case-Control Studies: Design, Conduct, Analysis. Oxford University Press. ISBN: 978-0195027815
Ďalšie názvyprospective study, follow-up study, longitudinal study, cohort studycase-control study, retrospective study, matched case-control, nested case-control
Príbuzné22
ZhrnutieA cohort study follows a group of individuals forward in time from exposure to outcome. Exposed and unexposed participants (or participants with differing exposure levels) are enrolled at baseline, characterized, and observed prospectively until the outcome occurs or the study ends. Cohort studies are fundamental to epidemiology and are the design of choice for establishing causal associations when randomized trials are infeasible or unethical.A case-control study identifies individuals with a disease or outcome (cases) and a comparison group without the outcome (controls), then measures prior exposure retrospectively. Developed in the 1950s–1970s by epidemiologists like Schlesselman and MacMahon, case-control studies are especially efficient for rare diseases, as they sample cases enriched for the outcome, avoiding the need for enormous cohorts. They are a mainstay of clinical epidemiology, observational research, and outbreak investigations.
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ScholarGatePorovnať metódy: Cohort Study Design · Case-Control Study Design. Získané 2026-06-17 z https://scholargate.app/sk/compare