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Байесовский анализ зависимости «доза-эффект»×Байесовская сеть×Логистическая регрессия×Анализ выживаемости×
ОбластьЭпидемиологияБайесовские методыСтатистика исследованийСтатистика исследований
СемействоProcess / pipelineBayesian methodsProcess / pipelineProcess / pipeline
Год появления1990s–2000s (Bayesian formalization)198819581958
Автор методаDeveloped from classical frequentist dose-response traditions; Bayesian formulations advanced by Dempster, Gelman, and colleaguesJudea PearlDavid Roxbee CoxEdward L. Kaplan and Paul Meier
ТипStatistical modeling approachProbabilistic graphical modelMethodMethod
Основополагающий источникGelman, A., Carlin, J. B., Stern, H. S., Dunson, D. B., Vehtari, A., & Rubin, D. B. (2013). Bayesian Data Analysis (3rd ed.). CRC Press. ISBN: 978-1439840955Pearl, J. (1988). Probabilistic Reasoning in Intelligent Systems: Networks of Plausible Inference. Morgan Kaufmann. ISBN: 978-1558604797Cox, D. R. (1958). The regression analysis of binary sequences. Journal of the Royal Statistical Society, Series B, 20(2), 215–242. DOI ↗Kaplan, E. L., & Meier, P. (1958). Nonparametric estimation from incomplete observations. Journal of the American Statistical Association, 53(282), 457–481. DOI ↗
Другие названияBayesian DRA, Bayesian dose-response modeling, Bayesian benchmark dose analysis, BDRBayes network, belief network, probabilistic graphical model, directed graphical modellogit model, binomial logistic regression, LRKaplan-Meier analysis, Cox regression, TTE analysis
Связанные3433
СводкаBayesian dose-response analysis models the relationship between the level of exposure (dose) to a substance and the magnitude or probability of a biological response, embedding that model in a Bayesian probabilistic framework. Unlike frequentist approaches that yield a single point estimate with confidence intervals, the Bayesian framework produces a full posterior distribution over model parameters, allowing explicit quantification of uncertainty, incorporation of prior scientific knowledge, and principled model averaging. It is widely applied in toxicology, pharmacology, environmental risk assessment, and clinical dose-finding studies.A Bayesian network is a probabilistic graphical model, introduced by Judea Pearl in 1988, that encodes a set of variables and their conditional dependencies as a directed acyclic graph (DAG). Each node represents a variable; each directed edge encodes a direct probabilistic influence. By combining Bayes' rule with the graph's conditional independence structure, the model supports reasoning under uncertainty — computing the probability of any variable given observed evidence about others.Logistic regression is a statistical method for modeling the probability of a binary outcome (disease present/absent, success/failure) as a function of continuous and categorical predictors. Developed by David Roxbee Cox (1958), it solves the problem of predicting categorical outcomes by applying a logistic transformation to constrain predictions to the [0,1] probability interval, enabling accurate risk stratification, diagnostic prediction, and causal inference in epidemiology, medicine, and social science.Survival analysis is a collection of statistical methods for modeling time from a defined starting point until an event of interest occurs (disease, recovery, death, equipment failure). Kaplan and Meier's nonparametric estimator (1958) and David Cox's proportional hazards model (1972) jointly enabled analysis of censored data—individuals whose event times are unknown because they left the study or were still event-free at follow-up. Indispensable in oncology, cardiology, infectious disease research, engineering reliability, and any field where time-to-event matters.
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ScholarGateСравнение методов: Bayesian Dose-Response Analysis · Bayesian Network · Logistic Regression · Survival Analysis. Получено 2026-06-18 из https://scholargate.app/ru/compare