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Bath Ankylosing Spondylitis Disease Activity Index (BASDAI)×Scorul de activitate a bolii 28 de articulații (DAS28)×Indicele de Activitate a Bolii Lupus Eritematos Sistemic 2000 (SLEDAI-2K)×
DomeniuReumatologieReumatologieReumatologie
FamilieProcess / pipelineProcess / pipelineProcess / pipeline
Anul apariției199419952002
Autorul originalGarrett et al.Prevoo et al.Gladman et al.
TipPatient-reported outcome (PRO)Clinician-ratedClinician-rated
Sursa seminalăGarrett S, Jenkinson T, Kennedy LG, Whitelock H, Gaisford P, Calin A. A new approach to defining disease status in ankylosing spondylitis: the Bath Ankylosing Spondylitis Disease Activity Index. The Journal of Rheumatology. 1994;21(12):2286-2291. link ↗Prevoo ML, Hart's AM, Van Houwelingen HC, et al. Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis & Rheumatism. 1995;38(1):44-48. DOI ↗Gladman DD, Ibañez D, Urowitz MB. Systemic Lupus Erythematosus Disease Activity Index 2000. The Journal of Rheumatology. 2002;29(2):288-291. link ↗
Denumiri alternativeBASDAI, BAS-DAIDAS28, DAS28-CRP, DAS28-ESRSLEDAI, SLEDAI-2K, SLE Disease Activity Index
Înrudite433
RezumatThe BASDAI is a patient-reported outcome measure of disease activity in ankylosing spondylitis (AS), a chronic inflammatory arthropathy affecting the spine and axial skeleton. Introduced by Garrett et al. in 1994, BASDAI uses six simple patient self-report items focused on the cardinal symptoms of AS: fatigue, spinal pain, peripheral joint involvement, and morning stiffness. As a PRO measure, BASDAI is practical for routine monitoring, responsive to treatment, and strongly associated with clinical outcomes and spinal damage progression, making it a cornerstone outcome in AS management and clinical trials.The DAS28 is a composite measure of rheumatoid arthritis (RA) disease activity, combining joint counts, inflammatory markers, and patient-reported global health. Developed in 1995 by Prevoo and colleagues, it has become the gold standard for monitoring RA activity in clinical trials and practice. It integrates objective clinical signs with laboratory and subjective assessment, providing a single numerical index of disease burden.The SLEDAI is a comprehensive clinician-assessed measure of systemic lupus erythematosus (SLE) disease activity, capturing manifestations across multiple organ systems (cutaneous, renal, neuropsychiatric, hematologic, and serological). Introduced by Bombardier et al. (1992) and refined as SLEDAI-2K by Gladman et al. (2002), SLEDAI uses weighted scoring of 24 clinical and laboratory features to quantify overall SLE activity. It is the most widely used outcome measure in SLE research and clinical trials, enabling standardised assessment of disease progression, flare prediction, and treatment response in this complex multisystem disease.
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ScholarGateCompară metode: Bath Ankylosing Spondylitis Disease Activity Index · Disease Activity Score 28 · Systemic Lupus Erythematosus Disease Activity Index. Preluat la 2026-06-18 de pe https://scholargate.app/ro/compare