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Análise de Sobrevida Prospectiva×Ensaio Clínico Randomizado (ECR)×
ÁreaEpidemiologiaEpidemiologia
FamíliaProcess / pipelineProcess / pipeline
Ano de origem1958–1972 (foundational methods); prospective design emphasis formalized by 1980s1948 (first rigorously conducted RCT — MRC streptomycin trial)
Autor originalKaplan & Meier (estimator, 1958); Cox (proportional hazards model, 1972); prospective design formalised in modern clinical epidemiologyAustin Bradford Hill; MRC Streptomycin Trial team
TipoLongitudinal observational or experimental study design with time-to-event analysisInterventional experimental study
Fonte seminalKleinbaum, D. G., & Klein, M. (2012). Survival Analysis: A Self-Learning Text (3rd ed.). Springer. ISBN: 978-1441966452Friedman, L. M., Furberg, C. D., DeMets, D. L., Reboussin, D. M., & Granger, C. B. (2015). Fundamentals of Clinical Trials (5th ed.). Springer. ISBN: 978-3319185385
Outros nomesprospective time-to-event analysis, prospective failure-time analysis, forward-looking survival study, prospective event-time studyRCT, randomized controlled trial, randomised controlled trial, clinical randomized trial
Relacionados56
ResumoProspective survival analysis is a longitudinal study design in which participants are enrolled before the event of interest occurs, followed forward in time under standardised conditions, and analysed using survival-analytic methods to estimate the time until a defined clinical endpoint — such as death, disease recurrence, or treatment failure. Because data are collected prospectively, exposure and covariate information are recorded before outcomes are known, substantially reducing recall and selection bias relative to retrospective approaches.A randomized clinical trial (RCT) is an experimental study design in which participants are randomly assigned to an intervention group or a control group, then followed prospectively to compare outcomes. Random allocation is the defining feature: it distributes known and unknown confounders across groups by chance, making the RCT the strongest individual study design for establishing causal efficacy of a treatment or intervention under controlled conditions.
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ScholarGateComparar métodos: Prospective Survival Analysis · Randomized clinical trial. Recuperado em 2026-06-19 de https://scholargate.app/pt/compare