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Estudo de Acurácia Diagnóstica Pareado×Estudo aninhado caso-controle×
ÁreaEpidemiologiaEpidemiologia
FamíliaProcess / pipelineProcess / pipeline
Ano de origem1990s–2000s (formalised with STARD 2003)1973–1977
Autor originalEvolved from matched case-control methodology; STARD standards formalised by Bossuyt et al. (2003)Nathan Mantel (1973); D. C. Thomas (1977 formalization)
TipoDiagnostic / clinical epidemiology study designHybrid observational study design
Fonte seminalBossuyt, P. M., Reitsma, J. B., Bruns, D. E., Gatsonis, C. A., Glasziou, P. P., Irwig, L. M., Lijmer, J. G., Moher, D., Rennie, D., & de Vet, H. C. W. (2003). Towards complete and accurate reporting of studies of diagnostic accuracy: The STARD initiative. BMJ, 326(7379), 41–44. DOI ↗Thomas, D. C. (1977). Addendum to: Methods of cohort analysis: Appraisal by application to asbestos mining. Journal of the Royal Statistical Society, Series A, 140(4), 469–491. link ↗
Outros nomesmatched DAS, paired diagnostic accuracy study, matched test accuracy study, matched sensitivity-specificity studyNCC study, nested CC design, case-control within cohort, density sampling case-control
Relacionados46
ResumoA matched diagnostic accuracy study evaluates how well an index test correctly identifies a target condition in study participants who have been matched on key characteristics — such as age, sex, or disease severity — to control for confounding. By pairing diseased and non-diseased subjects on relevant factors before administering the test, the design isolates the test's own discriminative performance from variation attributable to imbalanced covariates, yielding cleaner estimates of sensitivity, specificity, and related accuracy measures.A nested case-control study is an efficient observational design embedded within a defined cohort. For each participant who develops the outcome of interest (a case), a small number of matched controls are sampled from those still at risk at the same point in time. This density-sampling strategy yields odds ratios that approximate incidence-rate ratios from the full cohort at a fraction of the data-collection cost — making it the preferred alternative when measuring exposures for all cohort members would be prohibitively expensive or technically demanding.
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ScholarGateComparar métodos: Matched Diagnostic Accuracy Study · Nested case-control. Recuperado em 2026-06-15 de https://scholargate.app/pt/compare