Comparar métodos

	Comitê de Ética em Pesquisa	Princípios de Integridade na Pesquisa
Área	Ética em pesquisa	Ética em pesquisa
Família	Process / pipeline	Process / pipeline
Ano de origem	1974	2007
Autor original	U.S. Federal Requirement (National Research Act 1974); International adoption by WMA and research institutions globally	Multiple (National Academies, NIH/ORI, ESOMAR, individual discipline standards)
Tipo	Standard	Framework
Fonte seminal	U.S. Code of Federal Regulations, Title 45, Part 46: Protection of Human Subjects. Office of the Federal Register.	National Academies of Sciences, Engineering, and Medicine. (2017). Fostering Integrity in Research. The National Academies Press.
Outros nomes	IRB, Research Ethics Committee, REC	Responsible Conduct of Research, RCR, Research Ethics Standards
Relacionados	4	4
Resumo	The Institutional Review Board (IRB) is the independent ethics committee established at research institutions to review and approve human subjects research, ensuring compliance with ethical principles and federal regulations. Created as a legal requirement by the U.S. National Research Act (1974) and now adopted globally, the IRB serves as the primary mechanism for protecting research subjects while enabling legitimate research to proceed. No human subjects research can begin without IRB approval.	Research integrity encompasses the ethical and professional standards that guide responsible conduct in all aspects of research—from study design and data collection through analysis, reporting, and publication. The core principles—honesty, transparency, accountability, respect, and stewardship—ensure that research is trustworthy, reproducible, and contributes legitimate knowledge. These principles are universal across disciplines and are enforced through institutional policies, professional standards, and regulatory oversight. Violations of research integrity undermine scientific credibility and can harm subjects, institutions, and public trust.