Comparar métodos

	Desenho de Ensaio Cruzado	Delineamento Aleatorizado em Blocos Completos (RCBD)
Área	Delineamento experimental	Delineamento experimental
Família	Hypothesis test	Hypothesis test
Ano de origem	1960	1935
Autor original	Early formalized in clinical research literature; widely used since mid-20th century	Ronald A. Fisher
Tipo	Within-subject repeated-measures design	Parametric blocked ANOVA
Fonte seminal	Senn, S. (2002). Cross-over Trials in Clinical Research (2nd ed.). Wiley. ISBN: 978-0471496533	Montgomery, D.C. (2017). Design and Analysis of Experiments (9th ed.). Wiley. ISBN: 978-1-119-32093-7
Outros nomes	within-subject crossover, cross-over design, AB/BA design, Çapraz Desen (Crossover Design)	RCBD, randomized block design, complete block design, Tesadüf Bloklu Desen (RCBD)
Relacionados	6	6
Resumo	A crossover design is an experimental design in which each participant receives all treatments under investigation, but in a different sequence and across separate time periods. Each subject thus acts as their own control, which substantially reduces between-subject variability and allows efficient treatment comparisons with smaller sample sizes. The approach has been central to clinical pharmacology and comparative research since the mid-20th century, with foundational methodology codified by Senn (2002) and Jones & Kenward (2014).	The Randomized Complete Block Design (RCBD) is a parametric experimental design and hypothesis-testing framework that isolates and removes a known source of heterogeneity — called a block — before comparing treatment means. Introduced by Ronald A. Fisher in his 1935 monograph The Design of Experiments, it remains the foundational blocked design in agricultural, clinical, and industrial research.