Comparar métodos

	Regressão de Riscos Proporcionais de Cox	Modelo de Fragilidade Compartilhada para Dados de Sobrevivência Agrupados
Área	Análise de sobrevivência	Análise de sobrevivência
Família	Survival analysis	Survival analysis
Ano de origem	1972	1979
Autor original	Cox, D. R.	Vaupel, J.W., Manton, K.G. & Stallard, E.
Tipo	Semi-parametric hazard regression model	Random effects survival model
Fonte seminal	Cox, D. R. (1972). Regression Models and Life-Tables. Journal of the Royal Statistical Society: Series B, 34(2), 187–202.	Vaupel, J.W., Manton, K.G. & Stallard, E. (1979). The Impact of Heterogeneity in Individual Frailty on the Dynamics of Mortality. Demography, 16(3), 439–454.
Outros nomes	cox ph model, proportional hazards model, cox ph regression, Cox Orantılı Tehlikeler Regresyonu	shared frailty model, random effects survival model, Frailty Modeli (Paylaşılan Kırılganlık)
Relacionados	3	3
Resumo	Cox proportional hazards regression, introduced by D. R. Cox in 1972, is a semi-parametric model that estimates how one or more covariates affect the hazard — the instantaneous rate of experiencing an event — while leaving the baseline hazard function unspecified. It is the standard multivariable method in survival analysis and produces hazard ratios that quantify the relative risk associated with each predictor.	The shared frailty model, introduced by Vaupel, Manton, and Stallard in 1979, extends standard survival regression by incorporating a random effect — the 'frailty' — that captures unobserved heterogeneity among subjects or clusters. When survival outcomes are measured on individuals who share a common environment (patients in the same hospital, members of the same family, animals in the same litter), a frailty term accounts for the within-cluster dependence that ordinary Cox regression ignores.