Comparar métodos

	Experimento Laboratorial em Blocos	Ensaio Clínico Randomizado (ECR)
Área	Delineamento experimental	Delineamento experimental
Família	Process / pipeline	Hypothesis test
Ano de origem	1926–1935	1948
Autor original	Ronald A. Fisher	James Lind (early precursor, 1747); modern formulation: Austin Bradford Hill & Medical Research Council (1948)
Tipo	Controlled experimental design with blocking	Interventional comparative study
Fonte seminal	Fisher, R. A. (1935). The Design of Experiments. Oliver and Boyd.	Schulz, K.F., Altman, D.G., Moher, D., for the CONSORT Group (2010). CONSORT 2010 Statement: Updated Guidelines for Reporting Parallel Group Randomised Trials. BMJ, 340, c332.
Outros nomes	blocked lab experiment, laboratory randomized block design, RBD laboratory study, blocked within-lab experiment	RCT, randomised controlled trial, clinical trial, Randomize Kontrollü Çalışma (RCT) Tasarımı
Relacionados	5	7
Resumo	A blocked laboratory experiment is a controlled laboratory study in which experimental units are grouped into homogeneous blocks before treatment assignment, and treatments are then randomly assigned within each block. Blocking removes the influence of a known nuisance variable — such as participant batch, equipment run, or testing day — from the error term, increasing the precision of treatment comparisons without expanding sample size.	A randomized controlled trial (RCT) is the gold standard experimental design in clinical and health research, in which participants are randomly allocated to a treatment group or a control group so that the effect of an intervention can be measured with the highest possible degree of internal validity. The modern parallel-group RCT was formalized by Austin Bradford Hill and the Medical Research Council in their landmark streptomycin trial of 1948, and its reporting is governed today by the CONSORT 2010 guidelines (Schulz et al., 2010).