Multi-period Interrupted Time Series
Multi-period Interrupted Time Series (MITS) extends the classic ITS framework to settings where two or more interventions occur at known time points within the same series. By fitting a segmented regression with multiple breakpoints, MITS estimates the level change and slope change attributable to each intervention while controlling for the underlying secular trend and for the effects of earlier interruptions.
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- Kontopantelis, E., Doran, T., Springate, D. A., Buchan, I., & Reeves, D. (2015). Regression based quasi-experimental approach when randomisation is not an option: interrupted time series analysis. BMJ, 350, h2750. · DOI 10.1136/bmj.h2750
- Bernal, J. L., Cummins, S., & Gasparrini, A. (2017). Interrupted time series regression for the evaluation of public health interventions: a tutorial. International Journal of Epidemiology, 46(1), 348-355. · DOI 10.1093/ije/dyw098
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