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Risico-gecorrigeerde diagnostische nauwkeurigheidsstudie×ROC-analyse (Receiver Operating Characteristic)×
VakgebiedEpidemiologieStatistiek
FamilieProcess / pipelineHypothesis test
Jaar van ontstaanConceptual roots 1980s–1990s; covariate-adjusted ROC formally introduced 20091954 (signal detection); 1982 (AUC formalization)
GrondleggerMargaret Pepe and colleagues; covariate-adjusted ROC formalized by Janes & Pepe (2009)Peterson, Birdsall & Fox (signal detection theory); Hanley & McNeil (medical statistics)
TypeObservational clinical study design with covariate adjustmentDiagnostic accuracy evaluation
Oorspronkelijke bronPepe, M. S. (2003). The Statistical Evaluation of Medical Tests for Classification and Prediction. Oxford University Press. ISBN: 978-0198509844Hanley, J. A., & McNeil, B. J. (1982). The meaning and use of the area under a receiver operating characteristic (ROC) curve. Radiology, 143(1), 29–36. DOI ↗
Aliassencase-mix-adjusted diagnostic accuracy, stratified diagnostic accuracy study, covariate-adjusted diagnostic accuracy, risk-stratified DTA studyROC curve analysis, AUC analysis, sensitivity-specificity analysis, diagnostic accuracy analysis
Verwant64
SamenvattingA risk-adjusted diagnostic accuracy study evaluates how well an index test identifies a target condition while explicitly accounting for patient-level risk factors that influence either disease prevalence or test performance. By adjusting for case-mix, it yields accuracy estimates — sensitivity, specificity, and AUC — that are not confounded by the composition of the study sample, enabling fairer comparisons across populations and clinical settings.ROC analysis evaluates how well a continuous or ordinal test variable discriminates between two binary outcome classes. By plotting the true positive rate (sensitivity) against the false positive rate (1 − specificity) across all decision thresholds, it produces a curve whose area under the curve (AUC) quantifies overall discriminative power, ranging from 0.5 (chance) to 1.0 (perfect discrimination).
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ScholarGateMethoden vergelijken: Risk-adjusted diagnostic accuracy study · ROC analysis. Geraadpleegd op 2026-06-18 via https://scholargate.app/nl/compare