Methoden vergelijken

	Poweranalyse voor overlevingsstudies	Simulatiegebaseerde poweranalyse (Monte Carlo Power)
Vakgebied	Statistiek	Statistiek
Familie	Hypothesis test	Hypothesis test
Jaar van ontstaan	1981	2011
Grondlegger	—	Arnold et al. (2011); Green & MacLeod (2016) for mixed-model extension
Type	Sample size determination for survival outcomes	Simulation-based (Monte Carlo)
Oorspronkelijke bron	Schoenfeld, D. A. (1981). The asymptotic properties of nonparametric tests for comparing survival distributions. Biometrika, 68(1), 316–319.	Arnold, B.F. et al. (2011). Simulation Methods to Estimate Design Power: An Overview for Applied Research. BMC Medical Research Methodology, 11, 94.
Aliassen	log-rank power analysis, cox regression power analysis, survival power analysis, Sağkalım Analizi Güç Analizi	Monte Carlo power analysis, Monte Carlo simulation power, MC power, Simülasyon Tabanlı Güç Analizi (Monte Carlo Power)
Verwant	6	6
Samenvatting	Power analysis for survival studies determines how many participants — and how many observed events — are required so that a log-rank test or Cox regression has a sufficient probability of detecting a clinically meaningful difference in survival between groups. The foundational formulas were derived by Schoenfeld (1981) and Lachin (1981) and remain the standard approach in clinical trial planning.	Simulation-based power analysis estimates the statistical power and required sample size of a study by repeating a full analysis pipeline thousands of times on artificially generated data. Because it relies on Monte Carlo simulation rather than closed-form equations, it is applicable to designs — mixed models, complex measurement structures, non-standard outcomes — where analytical power formulas do not exist. The approach was systematically described for applied research by Arnold et al. in 2011, and the mixed-model implementation via the SIMR package was formalised by Green and MacLeod in 2016.