Methoden vergelijken

	Optimalisatie-ondersteunde Response Surface Methodology	Centraal Composite Ontwerp
Vakgebied	Experimenteel ontwerp	Experimenteel ontwerp
Familie	Process / pipeline	Process / pipeline
Jaar van ontstaan	1951 (RSM); 1980 (desirability-function optimization formalized)	1951
Grondlegger	Derringer & Suich (desirability function); Box & Wilson (RSM foundation)	George E. P. Box and K. B. Wilson
Type	Hybrid experimental-optimization framework	Response surface experimental design
Oorspronkelijke bron	Derringer, G., & Suich, R. (1980). Simultaneous optimization of several response variables. Journal of Quality Technology, 12(4), 214–219.	Box, G. E. P., & Wilson, K. B. (1951). On the experimental attainment of optimum conditions. Journal of the Royal Statistical Society: Series B, 13(1), 1–45.
Aliassen	OA-RSM, RSM with optimization, desirability-based RSM, multi-response RSM optimization	CCD, Box-Wilson design, central composite response surface design, rotatable central composite design
Verwant	5	3
Samenvatting	Optimization-assisted RSM couples a second-order response surface model with a mathematical optimization routine — most commonly Derringer and Suich's desirability function, but also genetic algorithms or gradient-based solvers — to locate the factor settings that simultaneously satisfy multiple quality or performance objectives. The result is a data-driven recommendation for optimal process or product conditions, supported by a polynomial model fitted to a structured experimental design.	Central Composite Design (CCD) is a second-order response surface design that allows researchers to efficiently fit a full quadratic model relating multiple continuous input factors to one or more response variables. Introduced by Box and Wilson in 1951, it combines a factorial (or fractional factorial) core, axial (star) points, and center-point replicates into a single unified design, making it the most widely used design for process optimization in engineering, chemistry, and manufacturing.