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Marginaal Structureel Model (MSM)×G-Computatie (Parametrische G-formule)×
VakgebiedCausale inferentieCausale inferentie
FamilieRegression modelRegression model
Jaar van ontstaan20001986
GrondleggerJames M. Robins, Miguel A. Hernan, Babette BrumbackJames M. Robins
TypeCausal model / semiparametric weightingParametric causal effect estimation
Oorspronkelijke bronRobins, J. M., Hernan, M. A., & Brumback, B. (2000). Marginal structural models and causal inference in epidemiology. Epidemiology, 11(5), 550-560. DOI ↗Robins, J. M. (1986). A new approach to causal inference in mortality studies with sustained exposure periods: application to control of the healthy worker survivor effect. Mathematical Modelling, 7(9-12), 1393-1512. DOI ↗
AliassenMSM, MSM-IPTW, marginal structural Cox model, weighted structural modelG-formula, Parametric G-formula, Standardization
Verwant52
SamenvattingA marginal structural model is a causal modeling framework designed to estimate the effect of a time-varying treatment in the presence of time-varying confounders that are themselves affected by prior treatment. By reweighting observations with inverse probability of treatment weights, MSMs create a pseudo-population in which confounding is eliminated, enabling unbiased estimation of causal treatment contrasts even when standard regression adjustments would fail.G-computation is a causal inference method for estimating the effect of an intervention or treatment on an outcome from observational data. Developed by James M. Robins in 1986, it provides a parametric approach to standardization that can handle time-varying exposures and confounders. The method estimates what the population outcome would be under different intervention scenarios by utilizing fitted outcome models.
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ScholarGateMethoden vergelijken: Marginal Structural Model · G-Computation. Geraadpleegd op 2026-06-15 via https://scholargate.app/nl/compare