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Adaptief Solomon Viergroepsontwerp×Gerandomiseerde gecontroleerde studie (RCT)×
VakgebiedExperimenteel ontwerpExperimenteel ontwerp
FamilieProcess / pipelineHypothesis test
Jaar van ontstaan1949 (base design); adaptive adaptation developed through later adaptive trial methodology1948
GrondleggerRichard L. Solomon (base design); adaptive extension via response-adaptive randomization methodologyJames Lind (early precursor, 1747); modern formulation: Austin Bradford Hill & Medical Research Council (1948)
TypeExperimental design (pretest-sensitization control + adaptive randomization)Interventional comparative study
Oorspronkelijke bronSolomon, R. L. (1949). An extension of control group design. Psychological Bulletin, 46(2), 137–150. DOI ↗Schulz, K.F., Altman, D.G., Moher, D., for the CONSORT Group (2010). CONSORT 2010 Statement: Updated Guidelines for Reporting Parallel Group Randomised Trials. BMJ, 340, c332. DOI ↗
Aliassenadaptive S4G design, response-adaptive Solomon design, sequential Solomon four-group design, adaptive pretest-sensitization designRCT, randomised controlled trial, clinical trial, Randomize Kontrollü Çalışma (RCT) Tasarımı
Verwant67
SamenvattingThe Adaptive Solomon Four-Group Design combines the pretest-sensitization control of Solomon's classic four-group structure with response-adaptive randomization, allowing interim outcome data to update the allocation probabilities across the four groups as the study progresses. This hybrid preserves the design's ability to isolate the testing effect while improving ethical efficiency by steering more participants toward conditions performing better at interim checkpoints.A randomized controlled trial (RCT) is the gold standard experimental design in clinical and health research, in which participants are randomly allocated to a treatment group or a control group so that the effect of an intervention can be measured with the highest possible degree of internal validity. The modern parallel-group RCT was formalized by Austin Bradford Hill and the Medical Research Council in their landmark streptomycin trial of 1948, and its reporting is governed today by the CONSORT 2010 guidelines (Schulz et al., 2010).
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ScholarGateMethoden vergelijken: Adaptive Solomon Four-Group Design · Randomized Controlled Trial. Geraadpleegd op 2026-06-19 via https://scholargate.app/nl/compare