Epigenome-wide association study in educational research
An epigenome-wide association study (EWAS) applied to educational research scans DNA methylation levels at hundreds of thousands of CpG sites across the genome to identify loci whose methylation is statistically associated with educational attainment, cognitive ability, or related learning outcomes. By linking blood- or saliva-derived methylation profiles with school records or psychometric scores, EWAS offers a molecular window into how biological and environmental exposures may shape educationally relevant traits across the lifespan.
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- Rakyan, V. K., Down, T. A., Balding, D. J., & Beck, S. (2011). Epigenome-wide association studies for common human diseases. Nature Reviews Genetics, 12(8), 529–541. · DOI 10.1038/nrg3000
- Sugden, K., Hannon, E. J., Arseneault, L., Belsky, D. W., Broadbent, J. M., Corcoran, D. L., … Caspi, A. (2020). Patterns of reliability: Assessing the reproducibility of responses across participants in epigenome-wide association studies. Genome Biology, 21(1), 1–17. · URL
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