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Regresi Bahaya Berkadaran Cox Multipusat×Regresi Bahaya Berkadaran Cox×
BidangEpidemiologiEpidemiologi
KeluargaProcess / pipelineProcess / pipeline
Tahun asal1972 (Cox model); multicenter applications formalized 1980s–1990s1972
PengasasD. R. Cox (Cox PH model); multicenter extension developed through collaborative trial methodologySir David Roxbee Cox
JenisSemi-parametric survival regression for clustered dataSemi-parametric regression model
Sumber perintisCox, D. R. (1972). Regression models and life-tables. Journal of the Royal Statistical Society: Series B (Methodological), 34(2), 187–202. DOI ↗Cox, D. R. (1972). Regression models and life-tables. Journal of the Royal Statistical Society: Series B (Methodological), 34(2), 187–202. DOI ↗
Aliasmulticenter Cox regression, multisite Cox PH model, stratified Cox model across centers, multicenter survival regressionCox regression, Cox PH model, proportional hazards model, CPH
Berkaitan45
RingkasanMulticenter Cox proportional hazards regression extends the classic Cox PH model to studies conducted at two or more clinical sites or centers. It estimates the effect of predictors on time-to-event outcomes while explicitly accounting for clustering within centers, between-center heterogeneity, and potential differences in baseline hazard across sites. This design is standard practice in large multicenter RCTs and observational cohort studies in oncology, cardiology, and other clinical fields.The Cox proportional hazards model is a semi-parametric regression method that estimates the effect of one or more covariates on the hazard — the instantaneous rate of an event such as death, relapse, or failure — while making no assumption about the shape of the baseline hazard function. Introduced by David Cox in 1972, it is the dominant tool for multivariable survival analysis in clinical and epidemiological research.
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ScholarGateBandingkan kaedah: Multicenter Cox proportional hazards · Cox proportional hazards. Dicapai 2026-06-20 daripada https://scholargate.app/ms/compare