방법 증거 기록

Adaptive Randomized Controlled Trial

An adaptive randomized controlled trial (adaptive RCT) is an experimental design in which pre-specified rules allow modifications to the trial while it is ongoing — such as changing allocation ratios, dropping underperforming arms, or stopping early for efficacy or futility — based on accumulating interim data. These adaptations are planned before the trial starts and governed by statistical rules to preserve Type I error control and validity.

Sources recorded, not reviewed

원본 기록

방법의 원본 기록에서 그대로 복사된 인용입니다. 이로부터 수준별 검증이 추론되지 않습니다.

분류학적 방법 기록 · process-pipeline / experimental-design

Chow, S.-C., & Chang, M. (2008). Adaptive Design Methods in Clinical Trials. Chapman & Hall/CRC. · ISBN 978-1584887690
Berry, D. A. (2006). Bayesian clinical trials. Nature Reviews Drug Discovery, 5(1), 27–36. · DOI 10.1038/nrd1927

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관련 방법

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Taxonomic bucketAdaptive Experimentmachine-suggested · Relational suggestion, not evidence.See alsoBayesian Inferencemachine-suggested · Relational suggestion, not evidence.Taxonomic bucketFactorial Randomized Controlled Trialmachine-suggested · Relational suggestion, not evidence.Taxonomic bucketMulti-arm experimentmachine-suggested · Relational suggestion, not evidence.Used in the same domainRandomized Controlled Trialmachine-suggested · Relational suggestion, not evidence.See alsoSequential Analysismachine-suggested · Relational suggestion, not evidence.