手法を比較

	スパイクソーティング	MEG Source Localization
分野	神経画像学	神経画像学
系統	Process / pipeline	Process / pipeline
提唱年	2000	1972
提唱者	Kenneth Harris	David Cohen
種類	Neuronal activity classification pipeline	MEG neuroimaging analysis pipeline
原典	Harris, K. D., Csicsvari, J., Hirase, H., et al. (2016). Accuracy of tetrode spike separation as determined by simultaneous intracellular and extracellular recordings. Journal of Neurophysiology, 84(1), 401–414.	Hauk, O., Friston, K. J., & Leff, A. (2019). Functional neuroimaging of language: understanding the complex relationships between localization and function. Journal of Neurolinguistics, 50, 236–250.
別名	unit isolation, single-unit recording, electrophysiology clustering	MEG localization, magnetic source imaging, MSI
関連	3	3
概要	Spike sorting is an electrophysiological technique for identifying and isolating action potentials of individual neurons from extracellular electrical recordings. Central to single-unit neurophysiology, spike sorting assigns spikes recorded on electrode arrays to their neuron of origin, enabling study of individual neuron firing patterns, timing, and network interactions with single-cell resolution.	Magnetoencephalography (MEG) source localization is the inverse problem of estimating where in the brain neural currents originate from magnetic field measurements at the scalp. Introduced by David Cohen in 1972, MEG offers superior temporal resolution (milliseconds) and spatial specificity compared to EEG, as magnetic fields are less distorted by tissue conductivity, enabling researchers to pinpoint neural activity with high precision.