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SERS×円偏光二色性×
分野分光学分光学
系統Process / pipelineProcess / pipeline
提唱年19741969
提唱者Martin FleischmannJean-Claude Fasman
種類Vibrational spectroscopy techniqueSpectroscopic method
原典Fleischmann, M., Hendra, P. J., & McQuillan, A. J. (1974). Raman spectra of pyridine adsorbed at a silver electrode. Chemical Physics Letters, 26(2), 163-166. DOI ↗Greenfield, N. J., & Fasman, G. D. (1969). Computed circular dichroism spectra for protein secondary structures. Biochemistry, 8(10), 4108-4116. DOI ↗
別名Surface-enhanced Raman scattering, SERS spectroscopyCD spectroscopy, circular dichroism, CD analysis
関連33
概要Surface-Enhanced Raman Spectroscopy (SERS) amplifies weak Raman signals by many orders of magnitude when analyte molecules are adsorbed on specially prepared metal (typically silver or gold) nanostructured surfaces. Discovered by Fleischmann, Hendra, and McQuillan in 1974, SERS enables detection of vibrational signatures of single molecules and ultra-trace contaminants, revolutionizing analytical chemistry and forensics.Circular Dichroism (CD) spectroscopy measures the differential absorption of left- and right-circularly polarized light by optically active molecules, particularly proteins and nucleic acids. Introduced by Greenfield and Fasman in 1969, CD is a rapid, non-destructive technique for characterizing secondary structure (alpha-helix, beta-sheet), monitoring protein folding transitions, and assessing conformational changes in response to pH, temperature, or ligand binding.
ScholarGateデータセット
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  3. PUBLISHED
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ScholarGate手法を比較: SERS · Circular Dichroism. 2026-06-17に以下より取得 https://scholargate.app/ja/compare