手法を比較

	マッチドコホート研究	前向きコホート研究
分野	疫学	疫学
系統	Process / pipeline	Process / pipeline
提唱年	Mid-20th century; propensity-score variant 1983	1950s (systematic application); conceptual roots earlier
提唱者	Established practice; propensity-score matching formalized by Rosenbaum & Rubin (1983)	Richard Doll and Austin Bradford Hill (landmark application, 1951-1954); cohort methodology formalised by modern epidemiology textbooks
種類	Observational analytic study design	Observational longitudinal study design
原典	Rothman, K. J., Greenland, S., & Lash, T. L. (2008). Modern Epidemiology (3rd ed.). Lippincott Williams & Wilkins. ISBN: 978-0781755641	Rothman, K. J., Greenland, S., & Lash, T. L. (2008). Modern Epidemiology (3rd ed.). Lippincott Williams & Wilkins. ISBN: 978-0781755641
別名	matched follow-up study, paired cohort study, propensity-matched cohort, matched prospective study	longitudinal cohort study, prospective follow-up study, incidence study, prospective observational cohort
関連	5	6
概要	A matched cohort study is an observational design in which each exposed participant is paired with one or more unexposed counterparts who share key characteristics — such as age, sex, or comorbidity status — before both groups are followed forward in time to compare incident outcomes. Matching controls for measured confounders at the design stage, reducing bias that would otherwise require statistical adjustment alone.	A prospective cohort study assembles a group of participants who are free of the outcome of interest at baseline, measures their exposures, and then follows them forward in time to record who develops the outcome. By collecting exposure data before outcomes occur, it establishes a clear temporal sequence that supports causal inference — a major advantage over retrospective designs. It is the cornerstone observational method in epidemiology and clinical research.