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	磁気共鳴エラストグラフィ	OCT Angiography
分野	医用画像	医用画像
系統	Process / pipeline	Process / pipeline
提唱年	1995	2012
提唱者	Richard Muthupillai	Yali Jia
種類	MRI-based measurement of tissue stiffness	Optical imaging technique for vasculature visualization
原典	Muthupillai, R., Lomas, D. J., Rossman, P. J., et al. (1995). Magnetic resonance elastography by direct visualization of propagating acoustic strain waves. Science, 269(5232), 1854-1857.	Jia, Y., Tan, O., Tokayer, J., et al. (2012). Split-spectrum amplitude-decorrelation angiography with optical coherence tomography. Optics Express, 20(4), 4710-4725.
別名	MRE, elastography, tissue stiffness mapping	OCTA, OCT-A
関連	5	5
概要	Magnetic Resonance Elastography (MRE) is a non-invasive imaging technique that measures tissue stiffness by encoding the motion of acoustic shear waves into MRI signal and calculating the elastic modulus from wave propagation patterns. Developed by Muthupillai and colleagues in 1995, MRE enables quantitative assessment of tissue mechanics, particularly useful for diagnosing liver fibrosis, cardiac dysfunction, and neurological diseases. It has emerged as a non-invasive alternative to biopsy for staging hepatic fibrosis and is expanding into other organ systems.	Optical Coherence Tomography Angiography (OCTA) is a non-invasive imaging technique that visualizes the microvasculature in the retina and choroid by detecting motion contrast from flowing blood. Developed by Jia and colleagues in 2012, OCTA uses repeated OCT scans of the same tissue location to identify blood flow based on the decorrelation signal. It has become a critical diagnostic tool in ophthalmology for detecting retinal and macular diseases without requiring fluorescein injection.