手法を比較

	ヘマグルチネーション抑制試験	ELISA（Enzyme-Linked Immunosorbent Assay）
分野	獣医科学	獣医科学
系統	Process / pipeline	Process / pipeline
提唱年	1942	1971
提唱者	George K. Hirst	Eva Engvall and Peter Perlmann; independent parallel development by Anton Schuurs and Bauke van Weemen
種類	Serological diagnostic assay	Quantitative immunoassay
原典	Hirst, G. K. (1942). The quantitative determination of influenza virus and antibodies by means of red cell agglutination. Journal of Experimental Medicine, 75(1), 49–64.	Engvall, E., & Perlmann, P. (1971). Enzyme-linked immunosorbent assay (ELISA) quantitative assay of immunoglobulin G. Immunochemistry, 8(9), 871–874.
別名	HI assay, HAI test, haemagglutination inhibition test, HI test	enzyme immunoassay, EIA, solid-phase enzyme immunoassay, ELISA test
関連	1	2
概要	The Hemagglutination Inhibition (HI) Assay is a classical serological test used to detect and quantify antibodies against hemagglutinating viruses — most notably influenza and Newcastle disease virus — in animal and human serum. Widely employed in veterinary diagnostics, vaccine efficacy evaluation, and epidemiological surveillance, it relies on the principle that specific antibodies in serum will block a known quantity of virus from agglutinating red blood cells.	ELISA is a plate-based immunoassay technique that detects and quantifies proteins, antibodies, antigens, hormones, and other analytes in biological samples. Widely used in veterinary science, medicine, and food safety, it exploits the specificity of antibody–antigen binding coupled to an enzyme-driven colorimetric signal to deliver sensitive, reproducible measurements across large sample batches.