手法を比較

	クラスター化された生存データのための共有脆弱性モデル	カプラン・マイヤー生存時間推定量	生存曲線比較のためのログランク検定
分野	生存時間解析	生存時間解析	生存時間解析
系統	Survival analysis	Survival analysis	Survival analysis
提唱年	1979	1958	1966
提唱者	Vaupel, J.W., Manton, K.G. & Stallard, E.	Kaplan, E. L. & Meier, P.	Mantel, N.
種類	Random effects survival model	Non-parametric survival estimator	Non-parametric hypothesis test
原典	Vaupel, J.W., Manton, K.G. & Stallard, E. (1979). The Impact of Heterogeneity in Individual Frailty on the Dynamics of Mortality. Demography, 16(3), 439–454.	Kaplan, E. L. & Meier, P. (1958). Nonparametric Estimation from Incomplete Observations. Journal of the American Statistical Association, 53(282), 457–481.	Mantel, N. (1966). Evaluation of Survival Data and Two New Rank Order Statistics Arising in Its Consideration. Cancer Chemotherapy Reports, 50(3), 163–170.
別名	shared frailty model, random effects survival model, Frailty Modeli (Paylaşılan Kırılganlık)	product-limit estimator, km curve, kaplan-meier sağkalım analizi	Mantel log-rank test, Mantel-Cox test, log-rank sağkalım testi, Log-Rank Testi
関連	3	2	2
概要	The shared frailty model, introduced by Vaupel, Manton, and Stallard in 1979, extends standard survival regression by incorporating a random effect — the 'frailty' — that captures unobserved heterogeneity among subjects or clusters. When survival outcomes are measured on individuals who share a common environment (patients in the same hospital, members of the same family, animals in the same litter), a frailty term accounts for the within-cluster dependence that ordinary Cox regression ignores.	The Kaplan-Meier estimator, introduced by Kaplan and Meier in 1958, is a non-parametric method that estimates the survival curve — the probability of remaining event-free over time — from right-censored time-to-event data. The log-rank test is the companion procedure used to compare survival curves between groups.	The log-rank test, developed by Nathan Mantel in 1966, is a non-parametric hypothesis test that compares the overall survival experience of two or more groups throughout the entire follow-up period. It is the standard companion to Kaplan-Meier curves and determines whether observed differences between curves are statistically meaningful.