手法を比較

	等価性検定（TOST	独立標本t検定
分野	統計学	統計学
系統	Hypothesis test	Hypothesis test
提唱年	1987	1908
提唱者	Donald J. Schuirmann	Student (W. S. Gosset)
種類	Parametric equivalence test	Parametric mean comparison
原典	Schuirmann, D.J. (1987). A Comparison of the Two One-Sided Tests Procedure and the Power Approach for Assessing the Equivalence of Average Bioavailability. Journal of Pharmacokinetics and Biopharmaceutics, 15(6), 657–680.	Student (1908). The probable error of a mean. Biometrika, 6(1), 1–25.
別名	TOST, two one-sided tests, bioequivalence test, Eşdeğerlik Testi (TOST — Two One-Sided Tests)	student t-test, two-sample t-test, unpaired t-test, bağımsız örneklem t-testi
関連	5	4
概要	The equivalence test using the Two One-Sided Tests (TOST) procedure is a parametric hypothesis test designed to demonstrate that the difference between two group means falls within a pre-specified equivalence region ±Δ. Introduced by Schuirmann (1987) in the context of pharmaceutical bioequivalence, TOST reverses the logic of classical null-hypothesis testing: instead of trying to detect a difference, it provides positive evidence of similarity.	The independent samples t-test is a parametric hypothesis test that compares the means of two independent groups to decide whether they differ significantly. It builds on the t-distribution introduced by Student (W. S. Gosset) in 1908 and assumes the measured values are continuous, approximately normally distributed, and have equal variances.