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| EDSS: Kurtzke Expanded Disability Status Scale (拡張身体機能障害尺度)× | MDS-UPDRS× | NIHSS:National Institutes of Health Stroke Scale× | RMI: Rivermead Mobility Index× | |
|---|---|---|---|---|
| 分野 | 神経学 | 神経学 | 神経学 | 神経学 |
| 系統 | Process / pipeline | Process / pipeline | Process / pipeline | Process / pipeline |
| 提唱年≠ | 1983 | 2008 | 1989 | 1991 |
| 提唱者≠ | John F. Kurtzke | Christopher G. Goetz and Movement Disorder Society | Thomas Brott and NIH Stroke Study Group | Frank Collen, Derick Wade, and Rivermead Rehabilitation Centre |
| 種類≠ | Clinician-rated | Clinician-rated | Clinician-rated | Clinician-observed performance test |
| 原典≠ | Kurtzke, J. F. (1983). Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS). Neurology, 33(11), 1444-1452. DOI ↗ | Goetz, C. G., et al. (2008). Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS): Scale presentation and clinimetric testing results. Movement Disorders, 23(15), 2129-2170. DOI ↗ | Brott, T., Adams, H. P., Olinger, C. P., et al. (1989). Measurements of acute cerebral infarction: A clinical examination scale. Stroke, 20(7), 864-870. DOI ↗ | Collen, F. M., Wade, D. T., Robb, G. F., Bradshaw, C. M. (1991). The Rivermead Mobility Index: A further development of the Rivermead Motor Assessment. International Disability Studies, 13(2), 50-54. DOI ↗ |
| 別名 | Expanded Disability Status Scale | UPDRS | NIH Stroke Scale | Rivermead Mobility Index |
| 関連≠ | 4 | 5 | 5 | 5 |
| 概要≠ | The EDSS is the most widely used clinical disability rating scale in multiple sclerosis research and practice. Developed by John Kurtzke in 1983, it provides a 0-10 ordinal scale capturing disease severity across eight neurological functional systems and functional status. The EDSS remains the primary endpoint in MS clinical trials and longitudinal cohort studies, with decades of prognostic and comparative data worldwide. | The MDS-UPDRS is the gold-standard clinician-administered rating scale for assessing motor and non-motor manifestations of Parkinson's disease. Developed by the Movement Disorder Society in 2008 to enhance the original UPDRS, it measures disease severity across daily living, motor function, and treatment complications. Used globally in clinical trials, longitudinal cohort studies, and routine neurological practice. | The NIHSS is the standard acute stroke severity assessment tool used in emergency departments, stroke centers, and clinical trials worldwide. Developed by the NIH Stroke Study Group in 1989, the 15-item scale provides rapid, reproducible quantification of acute neurological deficit from ischemic or hemorrhagic stroke. NIHSS scores inform thrombolytic and thrombectomy eligibility, predict outcomes, and serve as primary endpoint in stroke intervention trials. | The Rivermead Mobility Index (RMI) is a brief, clinician-observed performance test of basic mobility abilities developed for assessing stroke and neurological rehabilitation outcomes. Published in 1991 by Frank Collen and colleagues at Rivermead Rehabilitation Centre (Oxford, UK), the 15-item index measures bed mobility, sitting/standing balance, transfers, and ambulation. The RMI is widely used in stroke units and rehabilitation settings to track functional recovery and predict discharge outcomes. |
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