手法を比較

	拡散 커토시스 イメージング (Diffusion Kurtosis Imaging, DKI)	NODDI
分野	神経画像学	神経画像学
系統	Process / pipeline	Process / pipeline
提唱年	2005	2012
提唱者	Jens Jensen	Hui Zhang
種類	Microstructural white matter analysis	Microstructural white matter mapping
原典	Jensen, J. H., Helpern, J. A., Ramani, A., et al. (2005). Diffusional kurtosis imaging: the quantification of non-Gaussian water diffusion by magnetic resonance imaging. Magnetic Resonance in Medicine, 53(6), 1432–1440.	Zhang, H., Schneider, T., Wheeler-Kingshott, C. A., & Alexander, D. C. (2012). NODDI: practical in vivo neurite orientation dispersion and density imaging of the human brain. NeuroImage, 61(4), 1000–1016.
別名	DKI, non-Gaussian diffusion, diffusion kurtosis	NODDI, neurite density mapping
関連	3	3
概要	Diffusion Kurtosis Imaging (DKI) is an advanced diffusion MRI technique that quantifies non-Gaussian diffusion of water molecules, providing detailed information about tissue microstructure beyond conventional diffusion tensor imaging. Introduced by Jensen and colleagues in 2005, DKI detects deviations from normal Gaussian diffusion, revealing information about cellular compartmentalization and fiber heterogeneity.	Neurite Orientation Dispersion and Density Imaging (NODDI) is a biophysical diffusion MRI model that quantifies microstructural properties of white matter: neurite density (axonal density), orientation dispersion (fiber coherence), and isotropic diffusion (free water or cerebrospinal fluid). Introduced by Zhang and colleagues in 2012, NODDI provides biologically interpretable metrics directly linking diffusion MRI signals to tissue microstructure.