手法を比較

	DEXA	OCT Angiography	PET動態モデリング
分野	医用画像	医用画像	医用画像
系統	Process / pipeline	Process / pipeline	Process / pipeline
提唱年	1987	2012	1983
提唱者	Harold Wahner	Yali Jia	Christoph Patlak
種類	X-ray-based bone density measurement	Optical imaging technique for vasculature visualization	Mathematical framework for tracer kinetics in PET imaging
原典	Kanis, J. A. (1994). Assessment of fracture risk and its application to screening for postmenopausal osteoporosis. World Health Organization Technical Report Series, 843, 1-129.	Jia, Y., Tan, O., Tokayer, J., et al. (2012). Split-spectrum amplitude-decorrelation angiography with optical coherence tomography. Optics Express, 20(4), 4710-4725.	Patlak, C. S., Blasberg, R. G., Fenstermacher, J. D. (1983). Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data. Journal of Cerebral Blood Flow & Metabolism, 3(1), 1-7.
別名	Dual X-ray absorptiometry, DXA, bone densitometry	OCTA, OCT-A	PET pharmacokinetics, Dynamic PET, PET compartmental modeling
関連	5	5	5
概要	Dual-Energy X-ray Absorptiometry (DEXA or DXA) is a non-invasive imaging technique that quantifies bone mineral density (BMD) by measuring the attenuation of X-rays at two different energies as they pass through bone and soft tissue. First developed by Wahner and colleagues in 1987, DEXA has become the gold standard for osteoporosis screening and fracture risk assessment. It is recommended by the World Health Organization for diagnosing osteoporosis and monitoring treatment response.	Optical Coherence Tomography Angiography (OCTA) is a non-invasive imaging technique that visualizes the microvasculature in the retina and choroid by detecting motion contrast from flowing blood. Developed by Jia and colleagues in 2012, OCTA uses repeated OCT scans of the same tissue location to identify blood flow based on the decorrelation signal. It has become a critical diagnostic tool in ophthalmology for detecting retinal and macular diseases without requiring fluorescein injection.	PET kinetic modeling is a quantitative analysis technique that tracks the temporal behavior of radioactive tracers in tissue to extract physiological parameters such as blood flow, metabolic rate, and receptor density. Established by Patlak, Logan, and Gunn in the 1980s and 1990s, kinetic modeling transforms raw PET time-activity curves into interpretable biological measures. It is widely used in neurology, oncology, and cardiology to assess disease severity, treatment response, and regional tissue function.