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| 関節活動性スコア28関節（DAS28）× | Routine Assessment of Patient Index Data 3 (RAPID3)× | |
|---|---|---|
| 分野 | リウマチ学 | リウマチ学 |
| 系統 | Process / pipeline | Process / pipeline |
| 提唱年≠ | 1995 | 2008 |
| 提唱者≠ | Prevoo et al. | Pincus et al. |
| 種類≠ | Clinician-rated | Patient-reported outcome (PRO) |
| 原典≠ | Prevoo ML, Hart's AM, Van Houwelingen HC, et al. Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis & Rheumatism. 1995;38(1):44-48. DOI ↗ | Pincus T, Bergman MJ, Sokka T, Roth SH, Swearingen C, Yazici Y. Activity of rheumatoid arthritis is similar in patients seen in a primary care physician-based practice and in an academic rheumatology-based practice. Arthritis Care Research. 2008;59(9):1229-1236. link ↗ |
| 別名≠ | DAS28, DAS28-CRP, DAS28-ESR | RAPID3, RAPID-3 |
| 関連 | 3 | 3 |
| 概要≠ | The DAS28 is a composite measure of rheumatoid arthritis (RA) disease activity, combining joint counts, inflammatory markers, and patient-reported global health. Developed in 1995 by Prevoo and colleagues, it has become the gold standard for monitoring RA activity in clinical trials and practice. It integrates objective clinical signs with laboratory and subjective assessment, providing a single numerical index of disease burden. | RAPID3 is a patient-reported outcome (PRO) measure of rheumatoid arthritis disease activity based on three simple self-report items: patient-counted swollen and tender joints and overall health assessment. Introduced by Pincus et al. in 2008, RAPID3 was designed for primary care and busy practices where joint examination is impractical or time-limited. Remarkably, RAPID3 correlates strongly with clinician-examined composite measures (DAS28, CDAI, SDAI) and predicts long-term radiographic progression equally well, making it a practical alternative for resource-limited settings and self-directed monitoring. |
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