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	Coalescent Theory	集団混合解析
分野	遺伝学	遺伝学
系統	Process / pipeline	Process / pipeline
提唱年	1982	2009
提唱者	John Kingman	David Alexander & Jonathan Novembre
種類	Stochastic process model	Clustering and inference method
原典	Kingman, J. F. C. (1982). The coalescent. Stochastic Processes and their Applications, 13(3), 235–248.	Alexander, D. H., Novembre, J., & Lange, K. (2009). Fast model-based estimation of ancestry in unrelated individuals. Genome Research, 19(9), 1655–1664.
別名	Kingman Coalescent, n-coalescent	Population structure inference, Ancestry analysis, ADMIXTURE
関連	4	4
概要	Coalescent theory is a probabilistic framework that traces the genealogical history of DNA sequences backward in time to their most recent common ancestor. Developed by John Kingman in 1982, this method forms the foundation of modern population genetics, enabling researchers to understand demographic events, estimate genetic parameters, and reconstruct evolutionary histories from modern genetic data.	Admixture analysis is a population genetics method that infers population structure and individual ancestry from multilocus genotype data. Originally developed by Pritchard, Stephens, and Donnelly (2000) and refined by Alexander, Novembre, and Lange (2009), admixture analysis reveals how genetic variation is distributed among populations and estimates the ancestry fractions of admixed individuals. This technique is essential for understanding human evolutionary history, detecting population stratification in genetic studies, and inferring individual ancestry.