手法を比較
選択した手法を並べて確認できます。異なる行はハイライト表示されます。
| ATR-FTIR× | 円偏光二色性× | |
|---|---|---|
| 分野 | 分光学 | 分光学 |
| 系統 | Process / pipeline | Process / pipeline |
| 提唱年≠ | 1961 | 1969 |
| 提唱者≠ | Joop Fahrenfort | Jean-Claude Fasman |
| 種類≠ | Vibrational spectroscopy technique | Spectroscopic method |
| 原典≠ | Harrick, N. J. (1960). Study of physics of internal reflection from metals. Journal of Physics and Chemistry of Solids, 13(2), 143-155. link ↗ | Greenfield, N. J., & Fasman, G. D. (1969). Computed circular dichroism spectra for protein secondary structures. Biochemistry, 8(10), 4108-4116. DOI ↗ |
| 別名 | ATR-IR, attenuated total reflectance, FTIR spectroscopy | CD spectroscopy, circular dichroism, CD analysis |
| 関連 | 3 | 3 |
| 概要≠ | Attenuated Total Reflectance (ATR) Fourier Transform Infrared (FTIR) spectroscopy is a variant of conventional FTIR that measures infrared absorption through evanescent-wave interrogation of samples in direct contact with a high-refractive-index crystal. Developed by Harrick and Fahrenfort in the 1960s, ATR-FTIR is now the dominant form of FTIR spectroscopy, enabling rapid, non-destructive characterization of organic compounds, polymers, coatings, and biological materials without extensive sample preparation. | Circular Dichroism (CD) spectroscopy measures the differential absorption of left- and right-circularly polarized light by optically active molecules, particularly proteins and nucleic acids. Introduced by Greenfield and Fasman in 1969, CD is a rapid, non-destructive technique for characterizing secondary structure (alpha-helix, beta-sheet), monitoring protein folding transitions, and assessing conformational changes in response to pH, temperature, or ligand binding. |
| ScholarGateデータセット ↗ |
|
|