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	Punteggio Sequential Organ Failure Assessment	Punteggio APACHE II
Campo	Valutazione clinica	Valutazione clinica
Famiglia	Process / pipeline	Process / pipeline
Anno di origine	1996	1985
Ideatore	Jean-Louis Vincent and Rui Moreno	William A. Knaus, et al.
Tipo	Organ dysfunction and sepsis assessment	ICU severity and mortality prediction
Fonte seminale	Vincent, J. L., Moreno, R., Takala, J., et al. (1996). The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfuncti on/failure. Intensive Care Medicine, 22(7), 707-710.	Knaus, W. A., Draper, E. A., Wagner, D. P., & Zimmerman, J. E. (1985). APACHE II: a severity of disease classification system. Critical Care Medicine, 13(10), 818-829.
Alias	SOFA, Sepsis-related Organ Failure Assessment	APACHE-II, APACHE2
Correlati	3	3
Sintesi	The Sequential Organ Failure Assessment (SOFA) score, introduced by Vincent and Moreno in 1996, is a 24-point daily assessment tool that quantifies organ dysfunction across six physiological systems in critically ill patients. It was adopted into the 2016 Sepsis-3 definitions and is now the international standard for identifying and grading sepsis-related organ failure.	The Acute Physiology and Chronic Health Evaluation (APACHE) II score, introduced by Knaus et al. in 1985, is a 71-point severity of illness classification system for critically ill patients. It combines acute physiological parameters, age, and chronic health status to predict intensive care unit (ICU) mortality, facilitating patient risk stratification and research standardization.