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| Studio prospettico di accuratezza diagnostica× | Disegno dello Studio di Accuratezza Diagnostica× | |
|---|---|---|
| Campo≠ | Epidemiologia | Ricerca clinica |
| Famiglia | Process / pipeline | Process / pipeline |
| Anno di origine≠ | Formalized 2000s; practice dates to mid-20th century | 2003-2015 |
| Ideatore≠ | Established through STARD initiative (Bossuyt, Reitsma et al., 2000s) | Bossuyt, Reitsma, and STARD group (2003); clinical epidemiology pioneers |
| Tipo≠ | Observational / evaluative study design | Research Design |
| Fonte seminale≠ | Bossuyt, P. M., Reitsma, J. B., Bruns, D. E., Gatsonis, C. A., Glasziou, P. P., Irwig, L., ... & Cohen, J. F. (2015). STARD 2015: an updated list of essential items for reporting diagnostic accuracy studies. BMJ, 351, h5527. DOI ↗ | Bossuyt, P. M., Reitsma, J. B., Bruns, D. E., Gatsonis, C. A., Glasziou, P. P., Irwig, L. M., ... & de Vet, H. C. (2003). Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative. Annals of Internal Medicine, 138(1), 40–44. DOI ↗ |
| Alias | prospective DTA study, prospective test accuracy study, forward-looking diagnostic study, prospective index test evaluation | diagnostic accuracy study, test accuracy, STARD, diagnostic evaluation |
| Correlati≠ | 6 | 2 |
| Sintesi≠ | A prospective diagnostic accuracy study enrolls participants before any test results are known and follows them forward in time to evaluate how well an index test (the test under evaluation) distinguishes individuals with and without a target condition, using a reference standard applied independently. Key accuracy metrics include sensitivity, specificity, positive and negative predictive values, and the area under the ROC curve. The prospective design reduces many biases inherent in retrospective test evaluations. | A diagnostic accuracy study evaluates how well a new diagnostic test (or biomarker, imaging modality, clinical assessment) detects the presence or absence of disease compared to a reference standard (gold standard). Standardized since 2003 by the STARD (Standards for Reporting of Diagnostic Accuracy Studies) initiative, diagnostic accuracy studies are fundamental to clinical medicine, determining whether and how new tests can improve patient diagnosis and treatment. |
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