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Studio di coorte prospettico×Studio Caso-Controllo×
CampoEpidemiologiaEpidemiologia
FamigliaProcess / pipelineProcess / pipeline
Anno di origine1950s (systematic application); conceptual roots earlier1950s (formal methodology); precursors in the 1920s
IdeatoreRichard Doll and Austin Bradford Hill (landmark application, 1951-1954); cohort methodology formalised by modern epidemiology textbooksJanet Lane-Claypon (early precursors, 1926); formalized by Brian MacMahon and Jerome Cornfield in the 1950s–1960s
TipoObservational longitudinal study designObservational analytic study design
Fonte seminaleRothman, K. J., Greenland, S., & Lash, T. L. (2008). Modern Epidemiology (3rd ed.). Lippincott Williams & Wilkins. ISBN: 978-0781755641Schlesselman, J.J. (1982). Case-Control Studies: Design, Conduct, Analysis. Oxford University Press. ISBN: 978-0195027860
Aliaslongitudinal cohort study, prospective follow-up study, incidence study, prospective observational cohortcase-referent study, case-control design, retrospective case-control, case-control analysis
Correlati66
SintesiA prospective cohort study assembles a group of participants who are free of the outcome of interest at baseline, measures their exposures, and then follows them forward in time to record who develops the outcome. By collecting exposure data before outcomes occur, it establishes a clear temporal sequence that supports causal inference — a major advantage over retrospective designs. It is the cornerstone observational method in epidemiology and clinical research.A case-control study is a retrospective observational design in which individuals who have developed a disease or outcome of interest (cases) are compared with individuals who have not (controls) to determine whether prior exposure to a putative risk factor differs between the two groups. The primary measure of association is the odds ratio, which approximates the relative risk when the outcome is rare. Case-control studies are especially efficient for investigating rare diseases and generating etiological hypotheses.
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ScholarGateConfronta i metodi: Prospective Cohort Study · Case-control study. Consultato il 2026-06-15 da https://scholargate.app/it/compare