Confronta i metodi

	Report di casi multicentrico	Report di caso retrospettivo
Campo	Epidemiologia	Epidemiologia
Famiglia	Process / pipeline	Process / pipeline
Anno di origine	Long-standing practice; CARE guidelines formalized 2013	19th century (formalized ~2013 with CARE guidelines)
Ideatore	Clinical medicine tradition; CARE guidelines by Gagnier et al.	Case reporting tradition in medicine (formalized by CARE guidelines, Riley et al., 2013)
Tipo	Observational descriptive study	Observational descriptive study
Fonte seminale	Gagnier, J. J., Kienle, G., Altman, D. G., Moher, D., Sox, H., & Riley, D. (2013). The CARE guidelines: Consensus-based clinical case reporting guideline development. Journal of Medical Case Reports, 7, 223.	Gagnier, J. J., Kienle, G., Altman, D. G., Moher, D., Sox, H., & Riley, D. (2013). The CARE guidelines: consensus-based clinical case reporting guideline development. Journal of Medical Case Reports, 7(1), 223.
Alias	multi-site case report, collaborative case report, multicentre case report, CARE multicenter report	retrospective case study, post-hoc case report, retrospective clinical case, case report
Correlati	4	4
Sintesi	A multicenter case report is a structured clinical document describing one or a very small number of unusual patients observed across two or more independent healthcare institutions. By pooling observations from multiple sites, it overcomes the rarity barrier that prevents any single center from documenting an unusual presentation, adverse event, or novel treatment response — producing a richer, more externally valid account than a single-center report can offer.	A retrospective case report is a detailed, structured narrative of a single patient's clinical presentation, diagnosis, management, and outcome, assembled from existing medical records after the clinical events have occurred. It is the most granular and accessible observational design in clinical medicine, serving primarily to document rare presentations, unexpected outcomes, novel treatments, or unusual drug reactions that would not otherwise enter the published literature.