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	Modified Early Warning Score	Punteggio di gravità della polmonite CURB-65	Punteggio qSOFA	Punteggio Sequential Organ Failure Assessment
Campo	Valutazione clinica	Valutazione clinica	Valutazione clinica	Valutazione clinica
Famiglia	Process / pipeline	Process / pipeline	Process / pipeline	Process / pipeline
Anno di origine	2001	2003	2016	1996
Ideatore	Christian P. Subbe, et al.	W. Staniford Lim, et al.	Sepsis-3 Taskforce	Jean-Louis Vincent and Rui Moreno
Tipo	Hospital ward deterioration warning system	Community-acquired pneumonia severity assessment	Rapid sepsis screening	Organ dysfunction and sepsis assessment
Fonte seminale	Subbe, C. P., Kruger, M., Rutherford, P., & Gemmel, L. (2001). Validation of a modified Early Warning Score in medical admissions. QJM: An International Journal of Medicine, 94(10), 521-526.	Lim, W. S., van der Eerden, M. M., Laing, R., et al. (2003). Defining community acquired pneumonia severity on presentation to hospital: an international derivation and validation study. Thorax, 58(5), 377-382.	Singer, M., Deutschman, C. S., Seymour, C. W., et al. (2016). The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA, 315(8), 801-810.	Vincent, J. L., Moreno, R., Takala, J., et al. (1996). The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfuncti on/failure. Intensive Care Medicine, 22(7), 707-710.
Alias	MEWS, Early warning score	CURB-65, Pneumonia severity	Quick SOFA, qSOFA	SOFA, Sepsis-related Organ Failure Assessment
Correlati	3	3	3	3
Sintesi	The Modified Early Warning Score (MEWS), introduced by Subbe et al. in 2001, is a 14-point alert system designed for rapid detection of clinical deterioration in hospitalized patients. It combines six vital sign and laboratory parameters to identify patients at high risk of rapid decline, enabling early intervention before critical events occur.	CURB-65, derived and validated by Lim et al. in 2003, is a 5-point severity of illness score for community-acquired pneumonia (CAP). It assesses confusion, urea nitrogen, respiratory rate, blood pressure, and age ≥65 years to stratify mortality risk and guide admission and treatment decisions.	The Quick Sequential Organ Failure Assessment (qSOFA) score, introduced by the Sepsis-3 taskforce in 2016, is a rapid 3-variable bedside screening tool for identifying non-ICU patients at high risk of sepsis-related mortality. It uses altered mentation, systolic hypotension, and tachypnea to quickly stratify patients without requiring laboratory testing.	The Sequential Organ Failure Assessment (SOFA) score, introduced by Vincent and Moreno in 1996, is a 24-point daily assessment tool that quantifies organ dysfunction across six physiological systems in critically ill patients. It was adopted into the 2016 Sepsis-3 definitions and is now the international standard for identifying and grading sepsis-related organ failure.