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	Punteggio Mayo per la Colite Ulcerosa	Indice di Attività della Malattia di Crohn
Campo	Gastroenterologia	Gastroenterologia
Famiglia	Process / pipeline	Process / pipeline
Anno di origine	1987	1976
Ideatore	Schroeder, K. W., Tremaine, W. J., and Ilstrup, D. M.	Best, W. R., Becktel, J. M., Singleton, J. W., and Kern, F.
Tipo	Clinician-rated	Clinician-rated
Fonte seminale	Schroeder, K. W., Tremaine, W. J., & Ilstrup, D. M. (1987). Coated oral 5-aminosalicylic acid therapy for mildly to moderately active ulcerative colitis. New England Journal of Medicine, 317(26), 1625–1629.	Best, W. R., Becktel, J. M., Singleton, J. W., & Kern, F. (1976). Development of a Crohn's disease activity index. National Cooperative Crohn's Disease Study. Gastroenterology, 70(3), 439–444.
Alias	Mayo Clinic Score, UC Mayo Score	CDAI
Correlati	4	4
Sintesi	The Mayo Score is a validated tool for assessing disease activity in ulcerative colitis, integrating clinical symptoms and endoscopic findings. Introduced by Schroeder and colleagues in 1987, it has become the reference standard for UC activity assessment in clinical trials and practice. The score combines stool frequency, rectal bleeding, overall physician global assessment, and endoscopic subscore into a single 0–12 scale.	The Crohn's Disease Activity Index (CDAI) is a comprehensive, weighted index for assessing disease activity in Crohn's disease. Developed in 1976 by Best and colleagues for the National Cooperative Crohn's Disease Study, the CDAI integrates eight clinical and laboratory variables into a single score ranging from <150 (remission) to >450 (severe activity). Although more complex than symptom-based tools, the CDAI captures the multidimensional nature of Crohn's disease and remains the reference standard for severe disease assessment.