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	Scala di Valutazione della Depressione di Hamilton (HAM-D)	Questionario sulla Salute del Paziente-9 (PHQ-9)
Campo	Psicologia clinica	Psicologia clinica
Famiglia	Process / pipeline	Process / pipeline
Anno di origine	1960	2001
Ideatore	Max Hamilton	Kurt Kroenke
Tipo	Clinician-rated interview scale	Self-report questionnaire
Fonte seminale	Hamilton, M. (1960). A rating scale for depression. Journal of Neurology, Neurosurgery & Psychiatry, 23(1), 56–62.	Kroenke, K., Spitzer, R. L., & Williams, J. B. (2001). The PHQ-9: validity of a brief depression severity measure. Journal of General Internal Medicine, 16(9), 606–613.
Alias	HAM-D, HDRS, Hamilton Rating Scale for Depression	PHQ-9, Patient Health Questionnaire Depression Module
Correlati	5	5
Sintesi	The Hamilton Depression Rating Scale, published by Max Hamilton in 1960, is a clinician-administered interview assessment of depressive symptom severity. The most common version contains 17 items (HAM-D-17), though 21-item and 24-item versions exist. It is considered the gold standard outcome measure in antidepressant drug trials and remains the most cited depression rating scale in the psychiatric literature. Unlike self-report measures, HAM-D requires clinician judgment and observation, making it particularly valuable in research settings where standardized measurement by trained raters is essential.	The PHQ-9 is a brief, nine-item self-report questionnaire developed by Kroenke, Spitzer, and Williams to screen for and measure the severity of depressive symptoms. Published in 2001 in the Journal of General Internal Medicine, it has become one of the most widely used depression screening instruments globally. The scale maps directly to DSM-IV diagnostic criteria for major depressive disorder, making it valuable in both clinical and research settings.