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	Scala di Valutazione della Depressione di Hamilton (HAM-D)	Scala delle Impressioni Cliniche Globali (CGI)
Campo	Psicologia clinica	Psicologia clinica
Famiglia	Process / pipeline	Process / pipeline
Anno di origine	1960	1976
Ideatore	Max Hamilton	William Guy
Tipo	Clinician-rated interview scale	Clinician-rated assessment
Fonte seminale	Hamilton, M. (1960). A rating scale for depression. Journal of Neurology, Neurosurgery & Psychiatry, 23(1), 56–62.	Guy, W. (1976). ECDEU Assessment Manual for Psychopharmacology. Rockville, MD: National Institute of Mental Health, US Department of Health, Education, and Welfare.
Alias	HAM-D, HDRS, Hamilton Rating Scale for Depression	CGI, CGI-S, CGI-I
Correlati	5	4
Sintesi	The Hamilton Depression Rating Scale, published by Max Hamilton in 1960, is a clinician-administered interview assessment of depressive symptom severity. The most common version contains 17 items (HAM-D-17), though 21-item and 24-item versions exist. It is considered the gold standard outcome measure in antidepressant drug trials and remains the most cited depression rating scale in the psychiatric literature. Unlike self-report measures, HAM-D requires clinician judgment and observation, making it particularly valuable in research settings where standardized measurement by trained raters is essential.	The Clinical Global Impressions Scale is a clinician-administered two-part assessment developed by William Guy in the ECDEU Assessment Manual (1976) to provide rapid, global ratings of illness severity and treatment response. Part 1 (CGI-Severity) rates current severity; Part 2 (CGI-Improvement) rates change since treatment initiation. The CGI is among the most widely used global outcome measures in psychiatric research and clinical practice, prized for its brevity, interpretability, and ability to capture clinician expertise and nuanced clinical judgment.