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| Modello di Sopravvivenza Parametrico Flessibile (Royston-Parmar)× | Modello del Tempo di Fallimento Accelerato (AFT)× | |
|---|---|---|
| Campo | Analisi di sopravvivenza | Analisi di sopravvivenza |
| Famiglia | Survival analysis | Survival analysis |
| Anno di origine≠ | 2002 | 1992 |
| Ideatore≠ | Royston, P. & Parmar, M.K.B. | Wei, L. J. (seminal review 1992); origins in parametric survival literature |
| Tipo | Parametric survival regression model | Parametric survival regression model |
| Fonte seminale≠ | Royston, P. & Parmar, M.K.B. (2002). Flexible Parametric Proportional-Hazards and Proportional-Odds Models for Censored Survival Data, with Application to Prognostic Modelling and Estimation of Treatment Effects. Statistics in Medicine, 21(15), 2175–2197. DOI ↗ | Wei, L. J. (1992). The Accelerated Failure Time Model: A Useful Alternative to the Cox Regression Model in Survival Analysis. Statistics in Medicine, 11(14–15), 1871–1879. DOI ↗ |
| Alias≠ | flexible parametric model, restricted cubic spline survival model, stpm2, Esnek Parametrik Survival Modeli (Royston-Parmar) | AFT model, parametric survival regression, Hızlandırılmış Başarısızlık Zamanı Modeli (AFT) |
| Correlati≠ | 8 | 3 |
| Sintesi≠ | The Royston-Parmar model, introduced by Royston and Parmar in 2002, is a modern parametric approach to survival analysis that replaces the rigid distributional assumptions of classical models with a restricted cubic spline fitted to the log-cumulative-hazard scale. It combines the interpretability of a fully parametric model with the flexibility to capture non-standard hazard shapes, and it supports proportional-hazards, accelerated failure-time, and proportional-odds link functions. | The Accelerated Failure Time model is a parametric regression approach to survival analysis — formally reviewed and advocated by L. J. Wei in 1992 — in which covariates act as multiplicative factors that directly stretch or compress the time-to-event scale. Unlike the Cox proportional-hazards model, which models how covariates shift the hazard rate, AFT models express the covariate effect as an acceleration or deceleration of the time axis itself. |
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