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	CushQoL: Questionario sulla Qualità della Vita nella Sindrome di Cushing	ThyPRO: Scala per gli Esiti Riportati dai Pazienti Relativi alla Tiroide
Campo	Endocrinologia	Endocrinologia
Famiglia	Process / pipeline	Process / pipeline
Anno di origine	2008	2009
Ideatore	Sergio Webb, María D. Bernal, Juan M. Rivera-Caravaca	Torquil Watt, Jens Bjørner, Marianne Groenvold
Tipo	Patient self-report questionnaire	Patient self-report questionnaire
Fonte seminale	Webb, S. M., Bernal, M. D., Rivera-Caravaca, J. M., & Córdoba-Soriano, J. G. (2008). Development and validation of CushQoL, a disease-specific quality of life questionnaire in Cushing's syndrome. J Clin Endocrinol Metab, 93(5), 1751-1759.	Watt, T., Bjorner, J. B., Groenvold, M., et al. (2009). Establishing construct validity for the thyroid-related patient reported outcomes (ThyPRO): An initial examination. J Clin Endocrinol Metab, 94(9), 3572-3580.
Alias	Cushing QoL, CS-QoL	ThyPRO-85, ThyPRO-39
Correlati	3	3
Sintesi	CushQoL is a disease-specific 12-item quality of life questionnaire developed to assess the multidimensional impacts of Cushing's syndrome—a severe endocrine disorder characterized by excess cortisol production. Developed by Webb and colleagues in 2008, it captures physical symptoms (fatigue, weight gain, weakness, hirsutism), psychological manifestations (depression, anxiety, cognitive impairment), and social/occupational dysfunction unique to Cushing's syndrome. It is the standard outcome measure for assessing quality of life improvement following curative therapy.	ThyPRO is a comprehensive patient-reported outcome measure assessing the quality of life impact of thyroid disease and its treatment across 13 dimensions. Developed by Watt and colleagues in 2009, it is the most extensively validated thyroid-specific instrument, covering both physical and psychological domains relevant to patients with hyperthyroidism, hypothyroidism, and thyroid cancer.