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	Punteggio di gravità della polmonite CURB-65	Modified Early Warning Score	Punteggio Sequential Organ Failure Assessment
Campo	Valutazione clinica	Valutazione clinica	Valutazione clinica
Famiglia	Process / pipeline	Process / pipeline	Process / pipeline
Anno di origine	2003	2001	1996
Ideatore	W. Staniford Lim, et al.	Christian P. Subbe, et al.	Jean-Louis Vincent and Rui Moreno
Tipo	Community-acquired pneumonia severity assessment	Hospital ward deterioration warning system	Organ dysfunction and sepsis assessment
Fonte seminale	Lim, W. S., van der Eerden, M. M., Laing, R., et al. (2003). Defining community acquired pneumonia severity on presentation to hospital: an international derivation and validation study. Thorax, 58(5), 377-382.	Subbe, C. P., Kruger, M., Rutherford, P., & Gemmel, L. (2001). Validation of a modified Early Warning Score in medical admissions. QJM: An International Journal of Medicine, 94(10), 521-526.	Vincent, J. L., Moreno, R., Takala, J., et al. (1996). The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfuncti on/failure. Intensive Care Medicine, 22(7), 707-710.
Alias	CURB-65, Pneumonia severity	MEWS, Early warning score	SOFA, Sepsis-related Organ Failure Assessment
Correlati	3	3	3
Sintesi	CURB-65, derived and validated by Lim et al. in 2003, is a 5-point severity of illness score for community-acquired pneumonia (CAP). It assesses confusion, urea nitrogen, respiratory rate, blood pressure, and age ≥65 years to stratify mortality risk and guide admission and treatment decisions.	The Modified Early Warning Score (MEWS), introduced by Subbe et al. in 2001, is a 14-point alert system designed for rapid detection of clinical deterioration in hospitalized patients. It combines six vital sign and laboratory parameters to identify patients at high risk of rapid decline, enabling early intervention before critical events occur.	The Sequential Organ Failure Assessment (SOFA) score, introduced by Vincent and Moreno in 1996, is a 24-point daily assessment tool that quantifies organ dysfunction across six physiological systems in critically ill patients. It was adopted into the 2016 Sepsis-3 definitions and is now the international standard for identifying and grading sepsis-related organ failure.