Confronta i metodi
Esamina i metodi selezionati fianco a fianco; le righe che differiscono sono evidenziate.
| Esperimento multicentrico con disegno crossover× | Esperimento multi-braccio× | |
|---|---|---|
| Campo | Disegno sperimentale | Disegno sperimentale |
| Famiglia | Process / pipeline | Process / pipeline |
| Anno di origine≠ | Mid-20th century; multi-arm extensions formalized by 1970s–1980s | 1990s–2000s (clinical formalization); multi-arm concept implicit in ANOVA-era factorial designs |
| Ideatore≠ | Developed from early crossover trial methodology (Williams 1949; Cochran & Cox 1957) | Developed within clinical trials methodology; formalized by Parmar, Royston and colleagues (UK MRC CTU, early 2000s) |
| Tipo≠ | Within-subject experimental design with multiple treatment arms | Experimental design |
| Fonte seminale≠ | Jones, B., & Kenward, M. G. (2003). Design and Analysis of Cross-Over Trials (2nd ed.). Chapman and Hall/CRC. ISBN: 978-1584883869 | Royston, P., Parmar, M. K. B., & Qian, W. (2003). Novel designs for multi-arm clinical trials with survival outcomes with an application in ovarian cancer. Statistics in Medicine, 22(14), 2239–2256. DOI ↗ |
| Alias | multi-arm crossover trial, multi-period multi-treatment crossover, CMAT, multi-treatment crossover experiment | multi-arm trial, multiple-arm experiment, multi-group experiment, many-arm design |
| Correlati | 5 | 5 |
| Sintesi≠ | A crossover multi-arm experiment is a within-subject experimental design in which each participant receives three or more treatments (arms) across successive periods, with random assignment to sequence. Because every participant experiences all arms, the design eliminates between-subject variability from treatment comparisons, dramatically increasing statistical power for a given sample size. It is widely used in clinical pharmacology, psychology, agriculture, and behavioral research. | A multi-arm experiment simultaneously compares three or more treatment or intervention conditions — each called an arm — against a shared control or against one another. By testing multiple alternatives in a single study, it yields more information per participant than running separate two-group experiments sequentially, while controlling the overall Type I error rate through pre-specified comparison strategies. |
| ScholarGateInsieme di dati ↗ |
|
|