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	Progettazione Bayesiana di Esperimenti	Disegno Centrale Composito
Campo	Disegno sperimentale	Disegno sperimentale
Famiglia	Process / pipeline	Process / pipeline
Anno di origine	1956 (foundational); formalized 1970s–1990s	1951
Ideatore	Lindley (1956); Chaloner & Verdinelli (1995) landmark review	George E. P. Box and K. B. Wilson
Tipo	Bayesian optimal experimental design	Response surface experimental design
Fonte seminale	Chaloner, K., & Verdinelli, I. (1995). Bayesian Experimental Design: A Review. Statistical Science, 10(3), 273–304.	Box, G. E. P., & Wilson, K. B. (1951). On the experimental attainment of optimum conditions. Journal of the Royal Statistical Society: Series B, 13(1), 1–45.
Alias	Bayesian DOE, Bayesian optimal design, Bayesian experimental design, BDE	CCD, Box-Wilson design, central composite response surface design, rotatable central composite design
Correlati	3	3
Sintesi	Bayesian design of experiments selects experimental runs by maximising a utility function — typically the expected information gain — computed over prior beliefs about model parameters. Unlike classical design, which optimizes algebraic criteria such as D-optimality under fixed assumptions, Bayesian DOE incorporates prior knowledge and uncertainty about the system, yielding designs that are optimal in expectation across all plausible parameter values.	Central Composite Design (CCD) is a second-order response surface design that allows researchers to efficiently fit a full quadratic model relating multiple continuous input factors to one or more response variables. Introduced by Box and Wilson in 1951, it combines a factorial (or fractional factorial) core, axial (star) points, and center-point replicates into a single unified design, making it the most widely used design for process optimization in engineering, chemistry, and manufacturing.