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	Punteggio APACHE II	Modified Early Warning Score	Punteggio qSOFA
Campo	Valutazione clinica	Valutazione clinica	Valutazione clinica
Famiglia	Process / pipeline	Process / pipeline	Process / pipeline
Anno di origine	1985	2001	2016
Ideatore	William A. Knaus, et al.	Christian P. Subbe, et al.	Sepsis-3 Taskforce
Tipo	ICU severity and mortality prediction	Hospital ward deterioration warning system	Rapid sepsis screening
Fonte seminale	Knaus, W. A., Draper, E. A., Wagner, D. P., & Zimmerman, J. E. (1985). APACHE II: a severity of disease classification system. Critical Care Medicine, 13(10), 818-829.	Subbe, C. P., Kruger, M., Rutherford, P., & Gemmel, L. (2001). Validation of a modified Early Warning Score in medical admissions. QJM: An International Journal of Medicine, 94(10), 521-526.	Singer, M., Deutschman, C. S., Seymour, C. W., et al. (2016). The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA, 315(8), 801-810.
Alias	APACHE-II, APACHE2	MEWS, Early warning score	Quick SOFA, qSOFA
Correlati	3	3	3
Sintesi	The Acute Physiology and Chronic Health Evaluation (APACHE) II score, introduced by Knaus et al. in 1985, is a 71-point severity of illness classification system for critically ill patients. It combines acute physiological parameters, age, and chronic health status to predict intensive care unit (ICU) mortality, facilitating patient risk stratification and research standardization.	The Modified Early Warning Score (MEWS), introduced by Subbe et al. in 2001, is a 14-point alert system designed for rapid detection of clinical deterioration in hospitalized patients. It combines six vital sign and laboratory parameters to identify patients at high risk of rapid decline, enabling early intervention before critical events occur.	The Quick Sequential Organ Failure Assessment (qSOFA) score, introduced by the Sepsis-3 taskforce in 2016, is a rapid 3-variable bedside screening tool for identifying non-ICU patients at high risk of sepsis-related mortality. It uses altered mentation, systolic hypotension, and tachypnea to quickly stratify patients without requiring laboratory testing.