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क्षेत्रमहामारी विज्ञानअनुसंधान सांख्यिकी
परिवारProcess / pipelineProcess / pipeline
उद्भव वर्ष1950s–1980s (case-control design from 1950; risk-adjustment conventions established by 1980s)1958
प्रवर्तकDoll & Hill (foundational case-control); risk adjustment via multivariate logistic regression systematised by Schlesselman (1982) and Breslow & Day (1980)David Roxbee Cox
प्रकारObservational analytic study designMethod
मौलिक स्रोतSchlesselman, J. J. (1982). Case-Control Studies: Design, Conduct, Analysis. Oxford University Press. ISBN: 978-0195029697Cox, D. R. (1958). The regression analysis of binary sequences. Journal of the Royal Statistical Society, Series B, 20(2), 215–242. DOI ↗
उपनामadjusted case-control study, covariate-adjusted case-control, risk-stratified case-control study, matched and adjusted case-control studylogit model, binomial logistic regression, LR
संबंधित53
सारांशA risk-adjusted case-control study is an observational design that identifies individuals with a disease outcome (cases) and comparable individuals without it (controls), then uses statistical adjustment — most commonly multivariable logistic regression — to estimate the association between an exposure and the outcome while controlling for confounding risk factors. The adjustment step is what distinguishes this variant from a simple case-control study, producing odds ratios that better reflect the independent contribution of the exposure of interest.Logistic regression is a statistical method for modeling the probability of a binary outcome (disease present/absent, success/failure) as a function of continuous and categorical predictors. Developed by David Roxbee Cox (1958), it solves the problem of predicting categorical outcomes by applying a logistic transformation to constrain predictions to the [0,1] probability interval, enabling accurate risk stratification, diagnostic prediction, and causal inference in epidemiology, medicine, and social science.
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