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यादृच्छिक नैदानिक ​​परीक्षण (RCT)×उत्तरजीविता विश्लेषण×
क्षेत्रमहामारी विज्ञानअनुसंधान सांख्यिकी
परिवारProcess / pipelineProcess / pipeline
उद्भव वर्ष1948 (first rigorously conducted RCT — MRC streptomycin trial)1958
प्रवर्तकAustin Bradford Hill; MRC Streptomycin Trial teamEdward L. Kaplan and Paul Meier
प्रकारInterventional experimental studyMethod
मौलिक स्रोतFriedman, L. M., Furberg, C. D., DeMets, D. L., Reboussin, D. M., & Granger, C. B. (2015). Fundamentals of Clinical Trials (5th ed.). Springer. ISBN: 978-3319185385Kaplan, E. L., & Meier, P. (1958). Nonparametric estimation from incomplete observations. Journal of the American Statistical Association, 53(282), 457–481. DOI ↗
उपनामRCT, randomized controlled trial, randomised controlled trial, clinical randomized trialKaplan-Meier analysis, Cox regression, TTE analysis
संबंधित63
सारांशA randomized clinical trial (RCT) is an experimental study design in which participants are randomly assigned to an intervention group or a control group, then followed prospectively to compare outcomes. Random allocation is the defining feature: it distributes known and unknown confounders across groups by chance, making the RCT the strongest individual study design for establishing causal efficacy of a treatment or intervention under controlled conditions.Survival analysis is a collection of statistical methods for modeling time from a defined starting point until an event of interest occurs (disease, recovery, death, equipment failure). Kaplan and Meier's nonparametric estimator (1958) and David Cox's proportional hazards model (1972) jointly enabled analysis of censored data—individuals whose event times are unknown because they left the study or were still event-free at follow-up. Indispensable in oncology, cardiology, infectious disease research, engineering reliability, and any field where time-to-event matters.
ScholarGateडेटासेट
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  2. 2 स्रोत
  3. PUBLISHED
  1. v1
  2. 2 स्रोत
  3. PUBLISHED

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