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संभाव्य खुराक-प्रतिक्रिया विश्लेषण×कॉक्स प्रोपोर्शनल हैज़र्ड्स×
क्षेत्रमहामारी विज्ञानमहामारी विज्ञान
परिवारProcess / pipelineProcess / pipeline
उद्भव वर्ष1965 (Hill's criteria); widely applied through 1980s–present1972
प्रवर्तकBradford Hill (causal criteria including dose-response, 1965); formalized in modern epidemiology by Rothman, Greenland and othersSir David Roxbee Cox
प्रकारAnalytical epidemiological study designSemi-parametric regression model
मौलिक स्रोतRothman, K. J., Greenland, S., & Lash, T. L. (2008). Modern Epidemiology (3rd ed.). Lippincott Williams & Wilkins. ISBN: 978-0781755641Cox, D. R. (1972). Regression models and life-tables. Journal of the Royal Statistical Society: Series B (Methodological), 34(2), 187–202. DOI ↗
उपनामprospective exposure-response analysis, prospective trend analysis, forward-looking dose-response study, prospective gradient analysisCox regression, Cox PH model, proportional hazards model, CPH
संबंधित45
सारांशProspective dose-response analysis is an epidemiological approach that measures exposure levels in a defined population before outcomes occur, then quantifies how the risk or magnitude of an outcome changes systematically as exposure increases. By collecting exposure data prospectively, researchers can establish temporal sequence, reduce recall bias, and assess whether a biological gradient — one of Hill's classic causal criteria — exists between the agent of interest and a health outcome.The Cox proportional hazards model is a semi-parametric regression method that estimates the effect of one or more covariates on the hazard — the instantaneous rate of an event such as death, relapse, or failure — while making no assumption about the shape of the baseline hazard function. Introduced by David Cox in 1972, it is the dominant tool for multivariable survival analysis in clinical and epidemiological research.
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ScholarGateविधियों की तुलना करें: Prospective Dose-Response Analysis · Cox proportional hazards. 2026-06-19 को यहाँ से प्राप्त https://scholargate.app/hi/compare